संसाधन

Abatacept

Abatacept 2007 में रूमेटॉयड गठिया में उपयोग के लिए मंजूरी दे दी थी। यह शुरू में केवल जलसेक द्वारा उपलब्ध था, लेकिन उसकी अब भी सिरिंज या कलम के रूप में इंजेक्शन द्वारा उपयोग के लिए उपलब्ध है । यह टी-सेल को निशाना बनाता है।

फ़ोटो
Original Biologic drugBiosimilars (up-to-date at time of writing)प्रशासन की विधि
Abatacept (Orencia)N/AMonthly intravenous infusion or weekly subcutaneous (under the skin) injection

यह कैसे काम करता है?

As with other biologic drugs, Abatacept works by targeting proteins called cytokines, which are responsible for the inflammation caused by the immune system’s response. In the case of abatacept, the cytokines being targeted are called ‘T cells’.

सबसे अधिक रिपोर्ट किए गए दुष्प्रभाव

As with any medication, abatacept has a number of possible side effects, although it is important to remember that these are only potential side effects. They may not occur at all.

सामान्य दुष्प्रभावों में शामिल हो सकते हैं:

  • The most common side effects with abatacept are infections of the upper airway (including infections of the nose and throat)
  • headache and nausea

More information on side effects can be found in the patient information leaflet for abatacept. Remember to report any concerns about possible side effects to the doctors and nurses.


Abatacept with other medicines

Some biologic drugs are known to interact poorly with other biologics. You may therefore be asked to leave a gap between stopping one biologic drug and starting another, so that the first drug has time to start coming out of your system.

Abatacept during pregnancy and breastfeeding

Abatacept should not be used during pregnancy or while breastfeeding, due to limited data on safety. There is also not enough data to suggest that men can take this drug while their partner is trying to conceive.

Due to the possibility that the drug may cross the placenta during pregnancy, administration Original Biologic drug Biosimilars (up-to-date at time of printing) Method of administration Abatacept (Orencia) N/A Monthly intravenous infusion or weekly subcutaneous (under the skin) injection of live vaccines to infants exposed to abatacept in the womb is not recommended for 14 weeks following the mother’s last exposure to abatacept during pregnancy.

Pregnancy information in this booklet is based on British Society for Rheumatology (BSR) guidelines on prescribing drugs in pregnancy and breastfeeding.

Before starting a family it is recommended that you get advice from the consultant or clinical nurse specialist about when to start a pregnancy.

T-cell blockers and alcohol

You can drink alcohol on these medications. However, it is not uncommon when taking a biologic drug to be on other medications, where different guidance applies. Methotrexate, for example, can affect the liver, so for those taking methotrexate alongside their biologic, moderate intake of alcohol is recommended in line with government guidelines.

Abatacept and immunisations/ vaccinations

Live vaccines (measles, mumps, rubella i.e. MMR, chickenpox, oral polio (NOT injectable polio), BCG, oral typhoid and yellow fever) cannot be given to anyone already taking abatacept. If the treatment has not yet been started, it is important to seek advice on how long a gap to leave after having a live vaccine.

रुमेटी गठिया में दवाएं

हमारा मानना है कि यह आवश्यक है कि आरए के साथ रहने वाले लोगों को समझ क्यों कुछ दवाओं का उपयोग किया जाता है, जब वे इस्तेमाल कर रहे है और कैसे वे हालत का प्रबंधन काम करते हैं ।

ऑर्डर/डाउनलोड

Updated: 01/09/2020